abieta-7,13-dien-18-oic acid

abieta-7,13-dien-18-oic acid - Names and Identifiers

Name	Abietic acid
Synonyms	ABIETIC ACID Abietic acid abietic acid, technical abieta-7,13-dien-19-oate Abieticacid,TechnicalGrade abieta-7,13-dien-18-oic acid (9beta)-abieta-7,13-dien-19-oate (5beta)-abieta-7,13-dien-19-oate ABIETIC ACID MELTING POINT 153-167 C (5beta,9beta)-abieta-7,13-dien-19-oate (5xi,9xi)-abieta-7,13-dien-18-oic acid 13-isopropyl-podocarpa-13-dien-15-oicacid 13-isopropylpodocarpa-7,13-dien-15-oicacid (1R,4AR,4BR,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,4B,5,6,10,10A-DECAHYDRO-PHENANTHRENE-1-CARBOXYLIC ACID
CAS	514-10-3
EINECS	208-178-3
InChI	InChI=1/C20H30O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h7,12-13,16-17H,5-6,8-11H2,1-4H3,(H,21,22)/p-1/t16-,17-,19-,20+/m1/s1

abieta-7,13-dien-18-oic acid - Physico-chemical Properties

Molecular Formula	C20H30O2
Molar Mass	302.45
Density	1.06
Melting Point	139-142 °C (lit.)150-165 °C
Boling Point	440℃
Specific Rotation(α)	D24 -106° (c = 1 in abs alc)
Flash Point	208℃
Water Solubility	Soluble in acetone, petroleum ether, diethyl ether and ethanol. Insoluble in water.
Solubility	Easily soluble in ethanol, ether and other organic solvents. Slightly soluble in hot water, insoluble in cold water.
Vapor Presure	5.96E-09mmHg at 25°C
Appearance	yellowish or yellow-red vitreous
Color	Yellow-brownish
Exposure Limit	NIOSH: TWA 0.1 mg/m3
Merck	14,7
BRN	2221451
pKa	pK1:7.62 (25°C)
Storage Condition	2-8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Sensitive	Air Sensitive
Refractive Index	1.4800 (estimate)
MDL	MFCD03423567
Physical and Chemical Properties	This product is slightly yellow or yellow-red vitreous, softening point 72~74 ℃. Boiling point 300 C (666.6). Relative density (20 degrees C) 1.067. Refractive index 1.545 3 (20 °c), flash point 216 °c, ignition point 480~500 °c. Soluble in ethanol, ether and other organic solvents. Slightly soluble in hot water, insoluble in cold water.

abieta-7,13-dien-18-oic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 3077 9/PG 3
WGK Germany	3
RTECS	TP8580000
FLUKA BRAND F CODES	10-23
TSCA	Yes
HS Code	29162090
Hazard Class	9
Packing Group	III
Toxicity	LD50 ivn-mus: 180 mg/kg

abieta-7,13-dien-18-oic acid - Reference

Reference

1. Huang Xiaoyan, Li Tingting, Xiao Chunxia, et al. Quality evaluation of Styrax based on HPLC wavelength switching method for determination of seven components and chemometrics [J]. Chinese Journal of Traditional Chinese Medicine, 2019, 26 (14).
2. [IF = 3.738] Selma Houchi et al."Investigation of common chemical components and inhibition on GES-type β-lactamase (GES22)." Microb pathogensis. Jan 126

abieta-7,13-dien-18-oic acid - Nature

Open Data Verified Data

yellowish or yellow-red vitreous, insoluble in water, but soluble in organic solvents, such as acetone, ethyl ether, ethanol, ethyl acetate, turpentine, benzene and xylene. Rosin also has the crystallization characteristics, easy to produce crystallization phenomenon, in acetone and other organic solvents will have a crystallization trend, the crystallization critical temperature of about 100. In addition to its easy oxidation and isomerization reaction, it also has double bond reaction of disproportionation, hydrogenation, addition and polymerization. At the same time also with esterification, alcoholization, salt, decarboxylation, aminolysis and other carboxyl reaction.

Last Update：2024-01-02 23:10:35

abieta-7,13-dien-18-oic acid - Preparation Method

Open Data Verified Data

The Rosin removed from the pine tree is added into the reactor, heated and melted, and then water vapor is passed through, steam distillation is carried out, and the residual liquid of turpentine is distilled out, and filtered at about 210 ℃, the crystals were cooled to give a finished product. Alternatively, the pine pieces may be crushed, screened, and impregnated with gasoline, and the impregnated liquid may be filtered, decolorized, the solvent recovered, and distilled under reduced pressure to obtain a finished product.

Last Update：2022-01-01 09:30:50

abieta-7,13-dien-18-oic acid - Use

Open Data Verified Data

In the process of making paper used as sizing compound, can also be used as pesticide emulsifier, textile sizing agent, lubricant of building materials, plastic, rubber plasticizer, coating drying agent.

Last Update：2022-01-01 09:30:51

abieta-7,13-dien-18-oic acid - Safety

Open Data Verified Data

warehouse ventilation low temperature drying I and food raw materials separate storage and transportation.

Last Update：2022-01-01 09:30:51

abieta-7,13-dien-18-oic acid - Reference Information

EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
introduction	rosin acid is a tricyclic diterpenoid oxygenate. English name: Abietic acid rosin acid is soluble in lipids, slightly soluble in water, can react with glucose esterification, and can react with weak alkali saponification.
pharmacological properties	rosin acid is absorbed through intestinal tract through fat dissolution and emulsification by glucose. rosin acid and lipids entering blood have strong binding ability, decomposing lipids into small units. rosin acid enters human tissues with blood circulation. in body fluids, rosin acid and alkaline substances are saponified to generate rosin sodium and excreted with urine. The effect of rosin acid on lipids makes lipids approximate emulsification, lipid viscosity decreases, and deposited lipids are carried in a free state. The effect of rosin acid on body fluids keeps body fluids in an alkaline state due to the influence of sodium rosin, Increase the degree of emulsification.
indication	has significant curative effect on cardiovascular and cerebrovascular diseases, hypertension and diseases caused by acidic body fluids, and has obvious health care effect on maintaining alkaline constitution and improving comprehensive ability of body.
biological activity	Abietic acid is a diterpene compound extracted from Pimenta racemosa var. grissea, which has anti-proliferation, antibacterial and anti-obesity activities. Abietic acid inhibits lipoxygenase activity and is used in the study of allergic diseases.
Target	Value
PPARγ ()
5-lipoxygenase ()	29.5 μM
use	used as glue for gluing in the papermaking process, and can also be used as pesticide emulsifier, textile sizing agent, lubricant for building materials, plasticizer for plastics and rubber, and drier for coatings. The starting substance for the synthesis of natural products.
production method	take turpentine from live pine trees with turpentine as raw material, add the turpentine into a reactor, heat and melt, pass through water vapor, carry out steam distillation, evaporate the residual liquid of turpentine, filter at about 210 ℃, and cool and crystallize to obtain the finished product. Pine fragments are used as raw materials to crush, screen, impregnate with gasoline, then filter, decolorize, recover solvent, and distill the finished product under reduced pressure.
category	pesticide
acute toxicity	vein-mouse LD50:180 mg/kg
flammability hazard characteristics	flammability; heating decomposition releases stimulating smoke
storage and transportation characteristics	warehouse ventilation and low temperature drying; separate from food raw materials storage and transportation
fire extinguishing agent	dry powder, foam, sand

Last Update：2024-04-09 02:00:09

Jiangsu Pules Biotechnology Co.,Ltd.

abieta-7,13-dien-18-oic acid

Abietic acid

CAS: 514-10-3

Molecular Formula: C20H30O2

abieta-7,13-dien-18-oic acid - Names and Identifiers

abieta-7,13-dien-18-oic acid - Physico-chemical Properties

abieta-7,13-dien-18-oic acid - Risk and Safety

abieta-7,13-dien-18-oic acid - Reference

abieta-7,13-dien-18-oic acid - Nature

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abieta-7,13-dien-18-oic acid - Preparation Method

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abieta-7,13-dien-18-oic acid - Use

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abieta-7,13-dien-18-oic acid - Safety

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abieta-7,13-dien-18-oic acid - Reference Information

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abieta-7,13-dien-18-oic acid Request for Quotation

Abietic acid

CAS: 514-10-3

Molecular Formula: C20H30O2

abieta-7,13-dien-18-oic acid - Names and Identifiers

abieta-7,13-dien-18-oic acid - Physico-chemical Properties

abieta-7,13-dien-18-oic acid - Risk and Safety

abieta-7,13-dien-18-oic acid - Reference

abieta-7,13-dien-18-oic acid - Nature

Open Data Verified Data

abieta-7,13-dien-18-oic acid - Preparation Method

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abieta-7,13-dien-18-oic acid - Use

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abieta-7,13-dien-18-oic acid - Safety

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abieta-7,13-dien-18-oic acid - Reference Information

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abieta-7,13-dien-18-oic acid